Projects

Scientific secretary of IEFT, member of Executive board of CEM
Ing. Marta Šoltésová Prnová, PhD.

International

Finished
  • Multi-target paradigm for innovative ligand identification in the drug discovery process
    Program: COST
    Duration: 4. 12. 2015 – 29. 10. 2020
  • Targeting Molecular Pathways of Glucolipotoxicity by a Novel Carboxymethylated Mercaptotriazinoindole Inhibitor of Aldo-Keto Reductase AKR1B1 In Diabetes, Inflammation and Age-related Neurodegeneration
    Program: Bilateral - other
    Duration: 1. 5. 2016 – 30. 4. 2019
  • COST BM1204 : An integrated European platform for pancreas cancer research: from basic science to clinical and public health interventions for a rare disease
    Program: COST
    Duration: 16. 7. 2012 – 13. 12. 2016
  • COST CM1103 Structure-based drug design for diagnosis and treatment of neurological diseases
    Program: COST
    Duration: 28. 11. 2011 – 27. 11. 2015

National

Current
  • Aldo-keto reductase inhibitors in the personalized therapy of several types of cancer
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
  • A Public Platform for the Prediction of Toxic Substances Short title of the project/Acronym:
    Program:
    Duration: 1. 5. 2024 – 31. 12. 2025
  • Development of multifunctional aldose reductase inhibitors based on triazinoindoles: Optimization of their biological activity, selectivity, bioavailability and antioxidant properties.
    Program: VEGA
    Duration: 1. 1. 2022 – 31. 12. 2025
  • Multi-target approach to diverse molecular mechanisms of diabetic complications and other glucose toxicity related diseases
    Program: SRDA
    Duration: 1. 8. 2021 – 30. 6. 2025
Finished
  • Gut microbiota and diabetic peripheral neuropathy: effect of cemtirestat in rat models of diabetes
    Program: SRDA
    Duration: 1. 7. 2020 – 30. 6. 2024
  • Toxicology and pharmacology for everyone: How to protect yourself from risks in the 21st century
    Program: Other projects
    Duration: 1. 5. 2023 – 31. 12. 2023
  • Development of products by modification of natural compounds and study of their multi-modal effects onCOVID-19 disease
    Program:
    Duration: 1. 7. 2021 – 30. 6. 2023
  • Indole-1-acetic acid derivatives as aldose reductase inhibitors: structure – activity relationships
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2021
  • Novel compounds in prevention and treatment of diseases caused by glucose toxicity
    Program: VEGA
    Duration: 1. 1. 2018 – 31. 12. 2021
  • Redox Homeostasis, Proteostasis and Inflammation as Potential Targets For Influencing Ageing and Age-Related Diseases: Modulation by the compounds of natural and synthetic origin
    Program: VEGA
    Duration: 1. 1. 2017 – 31. 12. 2020
  • Pharmacological intervention in glucose-toxicity in type 2 diabetes
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2020
  • Multi-target paradigm for innovative ligand identification in the drug discovery process
    Program:
    Duration: 18. 4. 2016 – 17. 4. 2020
  • Aldo-keto reductases in chronic diseases – in silico modeling of significant enzymes and their complexes with indole derivatives
    Program: VEGA
    Duration: 1. 1. 2014 – 31. 12. 2017
  • MVTS An integrated European platform for pancreas cancer research: from basic science to clinical and public health interventions for a rare disease
    Program: Other projects
    Duration: 1. 6. 2013 – 13. 12. 2016
  • CM1103 Structure-based drug design for diagnosis and treatment of neurological diseases
    Program: Other projects
    Duration: 1. 1. 2014 – 27. 11. 2015
Employees