Projects

Senior Research Fellow
Ing. Ladislav Šoltés, DrSc.

International

Finished
  • Association of myeloperoxidase with hyaluronan. Implications for the pathophysiology of rheumatoid arthritis.
    Program: Bilateral - other
    Duration: 1. 1. 2009 – 31. 12. 2010
  • Degradative action of reactive oxygen species on hyaluronan: Degradation kinetics and molecular characteristics of generated hyaluronan fragments
    Program: Inter-academic agreement
    Duration: 1. 1. 2007 – 31. 12. 2009
  • Degradative Action of Reactive Oxygen Species on Hyaluronan: Degradation Kinetics and Molecular Characteristics of Generated Hyaloruronan Fragments
    Program: Inter-academic agreement
    Duration: 1. 1. 2007 – 31. 12. 2008
  • Comparative study of the degradation of high-molecular-weight hyaluronan by the action of myeoloperoxidase or by the direct action of hypochlorite/hypobromite
    Program: Inter-academic agreement
    Duration: 1. 1. 2005 – 31. 12. 2006

National

Current
  • In vitro study of antioxidative/antiinflammatory effects of natural and synthetic compounds. In vivo assessment of medicinal effects of selected compounds in experiments of healing skin wounds.
    Program: VEGA
    Duration: 1. 1. 2023 – 31. 12. 2027
Finished
  • New perspectives in the treatment of cardiovascular complications associated with COVID-19
    Program: SRDA
    Duration: 16. 9. 2020 – 31. 12. 2021
  • -
    Program: SRDA
    Duration: 1. 7. 2016 – 30. 6. 2020
  • Protective effects of natural and synthetic substances against oxidative damage of high-molar-mass hyaluronan, isolated mammal cells and their mitochondria
    Program: VEGA
    Duration: 1. 1. 2015 – 31. 12. 2018
  • Study of Actions of the Reactive Oxygen/Nitrogen Species on High-Molar-Mass Hyaluronan, Synoviocytes, and Chondrocytes
    Program: VEGA
    Duration: 1. 1. 2011 – 31. 12. 2014
  • -
    Program: SRDA
    Duration: 1. 5. 2011 – 31. 10. 2014
  • Early screening of anxiolytic and antidepressive properties of pyridoindole derivatives
    Program: VEGA
    Duration: 1. 1. 2009 – 31. 12. 2011
  • Hyaluronan degradation by reactive oxygen species: The reaction kinetics and molecular characteristics of generated polymer fragments
    Program: VEGA
    Duration: 1. 1. 2008 – 31. 12. 2010
  • Molecular mechanisms of new drugs influencing oxidative stress - important ethiopathogenetic factor of numerous diseases
    Program: SRDA
    Duration: 1. 9. 2006 – 31. 10. 2009
  • Hyaluronan-a relevant probe in testing the anti-oxidative properties of antiinflammatory and antirheumaticc drugs as well as of natural and synthetic antioxidants
    Program: VEGA
    Duration: 1. 1. 2005 – 1. 12. 2007